Research:2026-04-21/Journal article/three-closely-linked-x-chromosomal-genes-potentially-control-sex-determination-in-cannabis-sativa

ResearchJournal article21 April 2026

Three closely linked X-chromosomal genes potentially control sex determination in Cannabis sativa

Matteo Toscani, Afsheen Malik, Ainhoa Riera-Begue, Caroline A. Dowling, Quentin Rougemont, Ricardo C. Rodríguez de la Vega, Tatiana Giraud, Susanne Schilling, Rainer Melzer

New Phytologist

Combines quantitative trait locus mapping in a segregating population, transcriptomics comparing monoecious and dioecious cultivars, and an analysis of X-Y chromosome divergence to locate the genetic basis of sex determination in Cannabis sativa. The mapping identified Monoecy1, a locus on the X chromosome in the oldest and most diverged region of the sex chromosomes, holding three genes within 60,000 bp: CsREM16, lncREM16 and CsKAN4, each with distinct sex-specific and monoecy-specific expression. The authors propose that the interaction of these three genes accounts for both male-female and monoecious-dioecious sex determination. It pairs with the X-linked sex-determination study already recorded in this corpus.

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DOI10.1111/nph.71185

Record created 15 October 2026maintained by landrace.wiki editorspage history

2026-04-21 2026-10-15 Three closely linked X-chromosomal genes potentially control sex determination in Cannabis sativa Journal article Genetics Matteo Toscani, Afsheen Malik, Ainhoa Riera-Begue, Caroline A. Dowling, Quentin Rougemont, Ricardo C. Rodríguez de la Vega, Tatiana Giraud, Susanne Schilling, Rainer Melzer New Phytologist 2026 10.1111/nph.71185 https://doi.org/10.1111/nph.71185 Combines quantitative trait locus mapping in a segregating population, transcriptomics comparing monoecious and dioecious cultivars, and an analysis of X-Y chromosome divergence to locate the genetic basis of sex determination in Cannabis sativa. The mapping identified Monoecy1, a locus on the X chromosome in the oldest and most diverged region of the sex chromosomes, holding three genes within 60,000 bp: CsREM16, lncREM16 and CsKAN4, each with distinct sex-specific and monoecy-specific expression. The authors propose that the interaction of these three genes accounts for both male-female and monoecious-dioecious sex determination. It pairs with the X-linked sex-determination study already recorded in this corpus.